DECIPHER | Decellularised Extracellular Carpets for the Innovative Production of Human Engineered Replicates

Summary
The major roadblock in the commercialisation of cell-derived products is the prolonged ex vivo culture period required to develop them. Macromolecular crowding (MMC), a biophysical phenomenon that increases the kinetics of biochemical reactions and biological processes by several orders of magnitude, allows for the accelerated development of cell-derived products. This project will exploit MMC in the development of cell-derived products in 2 technical and 3 commercial work-packages, increasing the international competitiveness of European-based biotech industries and creating new employment, markets and revenue. This 18-months interdisciplinary and intersectoral project will train 1 post-doctoral researcher at the forefront of scientific research and technological innovation. The project will be carried out at University College Dublin, Ireland’s largest university, one of Europe’s leading research-intensive universities and in the top 1 % universities world-wide.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101138593
Start date: 01-01-2024
End date: 31-12-2025
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

The major roadblock in the commercialisation of cell-derived products is the prolonged ex vivo culture period required to develop them. Macromolecular crowding (MMC), a biophysical phenomenon that increases the kinetics of biochemical reactions and biological processes by several orders of magnitude, allows for the accelerated development of cell-derived products. This project will exploit MMC in the development of cell-derived products in 2 technical and 3 commercial work-packages, increasing the international competitiveness of European-based biotech industries and creating new employment, markets and revenue. This 18-months interdisciplinary and intersectoral project will train 1 post-doctoral researcher at the forefront of scientific research and technological innovation. The project will be carried out at University College Dublin, Ireland’s largest university, one of Europe’s leading research-intensive universities and in the top 1 % universities world-wide.

Status

SIGNED

Call topic

ERC-2023-POC

Update Date

12-03-2024
Geographical location(s)
Structured mapping
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EU-Programme-Call
Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2023-POC ERC PROOF OF CONCEPT GRANTS
HORIZON.1.1.1 Frontier science
ERC-2023-POC ERC PROOF OF CONCEPT GRANTS