microCrysFact | Microfluidic Crystal Factories (μ-CrysFact): a breakthrough approach for crystal engineering

Summary
To study and understand the aggregation, nucleation, and/or self-assembly processes of crystalline matter is of crucial importance for research and applications in many disciplines. For example, understanding the formation of crystalline amyloid fibres could lead to advances in the treatment and prevention of both Alzheimer’s and Parkinson’s diseases, whereas controlling the process of crystal formation can play a significant role in obtaining chemicals and materials that are important for industry as well as society as a whole (e.g., drugs, superconductors, polarizers and/or frequency modulators).

Despite the impressive progress made in molecular engineering during the last few decades, the quest for a general tool-box technology to study, control and monitor crystallisation processes as well as to isolate metastable states (dynamic capture) is still incomplete. That is because crystalline assemblies are frequently investigated in their equilibrium form, driving the system to its minimum energy state. This methodology limits the emergence of new chemicals and crystals with advanced functionalities, and thus hampers advances in the field of materials engineering.

µ-CrysFact will develop tool-box technologies where diffusion-limited and kinetically controlled environments will be achieved during crystallisation and where the isolation of non-equilibrium species will be facilitated by pushing crystallisation processes out of equilibrium. In addition, µ-CrysFact’s technologies will be used to localise, integrate and chemically treat crystals with the aim of honing their functionality. This unprecedented approach has the potential to lead to the discovery of new materials with advanced functions and unique properties, thus opening new horizons in materials engineering research.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/677020
Start date: 01-09-2016
End date: 31-08-2022
Total budget - Public funding: 1 814 128,00 Euro - 1 814 128,00 Euro
Cordis data

Original description

To study and understand the aggregation, nucleation, and/or self-assembly processes of crystalline matter is of crucial importance for research and applications in many disciplines. For example, understanding the formation of crystalline amyloid fibres could lead to advances in the treatment and prevention of both Alzheimer’s and Parkinson’s diseases, whereas controlling the process of crystal formation can play a significant role in obtaining chemicals and materials that are important for industry as well as society as a whole (e.g., drugs, superconductors, polarizers and/or frequency modulators).

Despite the impressive progress made in molecular engineering during the last few decades, the quest for a general tool-box technology to study, control and monitor crystallisation processes as well as to isolate metastable states (dynamic capture) is still incomplete. That is because crystalline assemblies are frequently investigated in their equilibrium form, driving the system to its minimum energy state. This methodology limits the emergence of new chemicals and crystals with advanced functionalities, and thus hampers advances in the field of materials engineering.

µ-CrysFact will develop tool-box technologies where diffusion-limited and kinetically controlled environments will be achieved during crystallisation and where the isolation of non-equilibrium species will be facilitated by pushing crystallisation processes out of equilibrium. In addition, µ-CrysFact’s technologies will be used to localise, integrate and chemically treat crystals with the aim of honing their functionality. This unprecedented approach has the potential to lead to the discovery of new materials with advanced functions and unique properties, thus opening new horizons in materials engineering research.

Status

CLOSED

Call topic

ERC-StG-2015

Update Date

27-04-2024
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EU-Programme-Call
Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.1. EXCELLENT SCIENCE - European Research Council (ERC)
ERC-2015
ERC-2015-STG
ERC-StG-2015 ERC Starting Grant