Report on cardiovascular developmental trajectories during fetal life, infancy and early childhood, and the relationship with early-life exposures and cardiovascular risk factors in childhood

We will use data from the EU Child Cohort Network partners that collected data before or during pregnancy and have detailed fetal and infant growth and cardiovascular development data. We will study associations of early-life stressors and the early-life exposome with adiposity and cardio-metabolic developmental trajectories in fetal life, infancy and early childhood (fetal and placental blood flow, cardiac and vascular dimensions, adiposity), and subsequently associations of these trajectories with risk factors for childhood for cardio-metabolic disease.