Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements

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Authors: Francesca E. Morreale, Andrea Testa, Viduth K. Chaugule, Alessio Bortoluzzi, Alessio Ciulli, Helen Walden

Journal title: Journal of Medicinal Chemistry

Journal number: 60/19

Journal publisher: American Chemical Society

Published year: 2017

Published pages: 8183-8191

DOI identifier: 10.1021/acs.jmedchem.7b01071

ISSN: 0022-2623