Periodic Reporting for period 5 - ICLUb (Regulation of DNA interstrand crosslink repair by ubiquitin.)

One of the most toxic types of DNA damage is when 2 strands of DNA become chemically linked to each other in an interstrand crosslink (ICL). Repair of ICLs involves a pathway of more than 20 proteins which cooperate to detect, remove, and repair the ICL. This pathway is called...