Periodic Reporting for period 3 - TroyCAN (Redefining the esophageal stem cell niche – towards targeting of squamous cell carcinoma)

In order to establish or maintain a tissue, stem cells need to balance the choice between self-renewal and differentiation. Stem cells reside in a complex microenvironment, or niche, that is instructive in determining cell fate. However, not all stem cell niches are...