Periodic Reporting for period 4 - PlasmoSilencing (Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing)

Our knowledge on malaria parasite posttranscriptional factors controlling expression of genes linked to severe malaria remains very limited. Our ground-breaking discovery of a mechanism that is a central player in this process via a new type of RNase-mediated gene silencing...