Periodic Reporting for period 1 - LySyT (Understanding the role of lysosomes in the intercellular TNT-mediated spreading of α-synuclein and the impact of lysosomal dysfunction)

Although neurodegenerative diseases (NDs) are one of the top 10 global causes of death, our knowledge about the basic molecular mechanisms underlying their pathogenesis is still lacking. The accumulation of misfolded protein aggregates in affected brain regions is a common...