Periodic Reporting for period 1 - EpiSeq (Single molecule sequencing and biophysical properties of oxidized genomic DNA using magnetic tweezers.)

Oxidative stress is a persistent threat to genomic DNA and RNA and is associated with major causes of human mortality, including cancers, diabetes and aging. 8-oxoguanine (8-oxoG) is the most common product of oxidative stress in nucleic acids. Evidence has accumulated to show...