Periodic Reporting for period 1 - BRCAstem (Monitoring cancer stem cell dynamics and therapeutic response in BRCA2-deficient breast tumour cells)

Mutations in the breast cancer susceptibility genes (BRCA) 1 and 2 lead to an increased susceptibility to breast, ovarian, and other types of cancers. In recent years, PARP inhibitors rapidly transformed the treatment of such cancers. As an anti-cancer drug, these inhibitors...