Periodic Reporting for period 1 - PI3K-in-tolerance (PI3K delta role in dendritic cell antigen processing and presentation to control gut tolerance)

Effective mammalian host defence against pathogenic microorganisms involve activation of dendritic cells (DCs) with potent priming ability to orchestrate adaptive T cell responses. Paradoxically within the intestine, the mammalian host encounters trillions of microbes and...