RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with<i>STMN-2</i>cryptic splicing and precedes clinical manifestation in ALS

Summary

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Authors: Holly Spence, Fergal M. Waldron, Rebecca S. Saleeb, Anna-Leigh Brown, Olivia M. Rifai, Martina Gilodi, Fiona Read, Kristine Roberts, Gillian Milne, Debbie Wilkinson, Judi O’Shaughnessy, Annalisa Pastore, Pietro Fratta, Neil Shneider, Gian Gaetano Tartaglia, Elsa Zacco, Mathew H. Horrocks, Jenna M. Gregory

Journal title: Acta Neuropathol

Journal number: 2024 Mar

Journal publisher: Springer

Published year: 2023

Published pages: 5;147

DOI identifier: 10.1101/2023.10.24.563701

ISSN: 1432-0533