Periodic Reporting for period 1 - EnhancemenT (Enhancing cytotoxic T-lymphocyte tumour-fighting capacity through the modulation of metabolic pathways regulated by ZFP36/ZFP36L1 RNA-binding proteins)

Cytotoxic CD8+ T-lymphocytes (CTLs) are a type of immune cell specialised in recognising and killing infected and tumour cells. This ability to kill cancer cells is also exploited in T-lymphocyte-based immunotherapies using chimeric antigen receptor (CAR) T-cells, where these...