ERD

Periodic Reporting for period 4 - NSC-Reconstruct (Novel Strategies for Cell-based Neural Reconstruction)

Project: NSC-Reconstruct

Updated at: 01-12-2025

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Project acronym NSC-Reconstruct

Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

<i>SREBP2</i> gene therapy targeting striatal astrocytes ameliorates Huntington’s disease phenotypes

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic or...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Brain cholesterol therapy for Huntington's disease – Does it make sense?

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

The history and status of dopamine cell therapies for Parkinson's disease

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Complete assessment of the therapeutic efficacy and potency of stem cell-derived MSNs

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Report on the ability of grafted human neurons to integrate and restore visual and motor dysfunction

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson’s Disease Patients ...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

To make defined MHC knock out hPSC derived neurons and study in animal models of disease

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Scaling of cell and gene therapies to population

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Report on the efficiency and specificity of inducing cortico-striatal projection neurons from local glia in vivo

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Report on the protocols and next-generation hPSC-derived or converted DA, MSN, cortical, telencephalic interneurons and ...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft-deriv...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Evaluation of graft enhancements for increased therapeutic effect, including non-DA dependent aspects

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral ...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Report on the ability of grafted programmed cells to undergo circuit integration in the adult rodent brain

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

First protocols for in vivo MSN reprogramming from glia

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral m...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

TGIF2 is a major regulator of neural stem cell fate and neurogenic priming

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprog...

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

Documentation of functional efficacy and circuitry integration of in situ converted DA neurons

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo

Project: NSC-Reconstruct

Updated at: 01-10-2025

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Project acronym NSC-Reconstruct

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