ERD

A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody-Drug Conjugates

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Immunocytokines and bispecific antibodies: two complementary strategies for the selective activation of immune cells at ...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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High-sensitivity HLA class I peptidome analysis enables a precise definition of peptide motifs and the identification of...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Project acronym ZAUBERKUGEL

Immunocytokines: a novel class of products for the treatment of chronic inflammation and autoimmune conditions

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Immunocytokines for cancer treatment: past, present and future

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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A universal reporter cell line for bioactivity evaluation of engineered cytokine products

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Periodic Reporting for period 4 - ZAUBERKUGEL (Fulfilling Paul Ehrlich’s Dream: therapeutics with activity on demand)

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Antibody–Cytokine Fusions: Versatile Products for the Modulation of Anticancer Immunity

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Comparative evaluation of bolus and fractionated administration modalities for two antibody-cytokine fusions in immunoco...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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DNA-Compatible Diazo-Transfer Reaction in Aqueous Media Suitable for DNA-Encoded Chemical Library Synthesis

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Acti...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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In Vivo Antitumor Activity of a Novel Acetazolamide–Cryptophycin Conjugate for the Treatment of Renal Cell Carcinomas

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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The antibody‐based delivery of interleukin‐12 to solid tumors boosts NK and CD8 + T cell activity and synergizes wit...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Design and characterisation of a novel interleukin-15 receptor alpha fusion protein and analysis of interleukin-15 compl...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling casca...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carci...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Non-internalizing antibody-drug conjugates display potent anti-cancer activity upon proteolytic release of monomethyl au...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Project acronym ZAUBERKUGEL

Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Intralesional treatment of metastatic melanoma: a review of therapeutic options

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Potentiation of PD-L1 blockade with a potency-matched dual cytokine–antibody fusion protein leads to cancer eradicatio...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Antibody-Based Delivery of Cytokine Payloads to Carbonic Anhydrase IX Leads to Cancer Cures in Immunocompetent Tumor-Bea...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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A novel dual-cytokine–antibody fusion protein for the treatment of CD38-positive malignancies

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Ca...

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Project acronym ZAUBERKUGEL

Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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Project acronym ZAUBERKUGEL

Antibody-cytokine fusion proteins: Biopharmaceuticals with immunomodulatory properties for cancer therapy

Project: ZAUBERKUGEL

Updated at: 27-04-2024

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