ERD

Publications on in silico PBPK models for predict in vivo performance of bio-enabling formulations

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

White paper on ‘Opportunities for Regulatory Bio-waivers using integrated PBPK/PD approaches.

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across Permeapa...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipi...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

A Novel Rheological Method to Assess Drug-Polymer Interactions Regarding Miscibility and Crystallization of Drug in Amor...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testin...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In‐vitro–in‐silico investigation of the negative food effect of zolpidem when administered as immediate‐release ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Broadband Diffusing Wave Spectroscopy Reveals Microstructuring of Polymer–Drug System

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Supersaturated lipid-based drug delivery systems – exploring impact of lipid composition type and drug properties on s...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispers...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Disposition of two highly permeable drugs in the upper gastrointestinal lumen of healthy adults after a standard high-ca...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersion...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory St...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

A Novel In Silico Screening Protocol For The Selection Of Optimized Precipitation Inhibitor Systems For Supersaturable F...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosag...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring the Impact of Surfactant Type and Digestion: Highly Digestible Surfactants Improve Oral Bioavailability of Nil...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring gastric emptying rate in mini-pigs: Effect of food type and pre-dosing of metoclopramide

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In Vitro Modelling Of Propranolol Immediate Release And Extended Release Formulations Using A Three Chamber Dissolution ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating ph...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofi...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silic...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-s...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

New Insights into Using Lipid Based Suspensions for ‘Brick Dust’ Molecules: Case Study of Nilotinib

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches - a PEARRL review

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

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